Hemodialysis Duration and Quality of Life Among Patients with Chronic Kidney Disease at Guido Valadares National Hospital, Dili Timor-Leste : A Cross-Sectional Study
Abstract
Introduction: Chronic kidney disease (CKD) represents a major global public health concern, with a rapidly increasing burden worldwide. According to the 2023 report by the International Society of Nephrology, approximately 850 million individuals globally are affected by CKD, with a median prevalence of 9.5% and a median mortality rate attributable to CKD of 2.4% (ISN, 2023). In the Asia region, the prevalence of CKD varies considerably, ranging from 7% to 34.3%. The regional burden is largely driven by highly populated countries, particularly China, with an estimated 159.8 million affected individuals (95% CI: 146.6–174.1), and India, accounting for approximately 140.2 million cases (95% CI: 110.7–169.7) (Liyanage et al., 2022). In Timor-Leste, CKD has emerged as a significant contributor to mortality, with an estimated mortality rate of 32.7 per 100,000 population, highlighting its substantial public health burden (WHO, 2021). In 2025, the Nephrology Unit of Hospital Nacional Guido Valadares reported a total of 114 active patients receiving regular haemodialysis therapy, indicating a substantial demand for renal replacement services at the national referral hospital (Medical Record HNGV, 2025). This study aims to examine the relationship between the duration of hemodialysis therapy and quality of life among patients with chronic kidney disease at the Nephrology Unit of Hospital Nacional Guido Valadares, Dili.
Method: This study was conducted at the Nephrology Unit of Hospital Nacional Guido Valadares, Dili, using a quantitative correlational approach with a cross-sectional design. A total of 89 participants were included, selected through non-probability sampling using a purposive sampling technique. Data were collected using the WHOQOL questionnaire to assess quality of life, and statistical analysis was performed using the Spearman Rank correlation test.
Result: The results demonstrated a statistically significant association between the duration of hemodialysis and quality of life among patients with chronic kidney insufficiency (r = 0.629; p < 0.05). The majority of respondents had undergone hemodialysis for more than 24 months (58 patients; 65.2%), and most participants were classified as having a high quality of life (54 patients; 60.7%).
Conclussion: identified a significant relationship between the duration of haemodialysis therapy and quality of life among patients with CKD. These findings indicate that the length of haemodialysis treatment is an important factor influencing patients’ quality of life.
Zenodo Doi:-10.5281/zenodo.19473952
Keywords
CKD, Dialysis Therapy Duration, Patient-Reported Outcomes, Health-Related Quality of Life (HRQoL)How to Cite
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Copyright (c) 2026 Joaquim Gregorio de Carvalho, Joaquim Pinto, Natalia Pereira, Eugenia Carvalho de Araújo, Ostelino da Silva Belo, Etelvina José Soares Tilman, Bernardina Freitas Pinto
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