Formulation and evaluation of silver nanoparticle of root extract of “pimenta dioica”

Section: Articles Published Date: 2024-06-06 Pages: 14-26 Views: 145 Downloads: 65

Authors

  • RAKESH THAKRE Research Scholar in Lakshmi Narain College of Pharmacy, Bhopal, (Madhya Pradesh), India
  • KAUSHELENDRA MISHRA Research Scholar in Lakshmi Narain College of Pharmacy, Bhopal, (Madhya Pradesh), India
  • RICHA VERMA Research Scholar in Lakshmi Narain College of Pharmacy, Bhopal, (Madhya Pradesh), India
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volume 07  issue 06

Abstract

This study aims to investigate the synthesis, characterization, and evaluation of silver nanoparticles (AgNPs) derived from the root extract of Pimenta dioica, a natural and sustainable source of reducing and stabilizing agents. The AgNPs were prepared through a green synthesis process, involving the reduction of silver ions by the phytochemicals present in the root extract. The synthesized AgNPs were characterized using various techniques, including UV-Vis spectroscopy and scanning electron microscopy (SEM), to determine their size and shape. The results revealed that the AgNPs exhibited a narrow size distribution, with an average size of 182.8 to 201.6 nm, and a spherical morphology. The antimicrobial activity of the synthesized AgNPs was evaluated against a bacterial strain, including Gram-positive bacteria. The results demonstrated that the AgNPs exhibited promising antimicrobial activity against the tested strain. The study highlights the potential applications of the AgNPs in various fields, including medicine and food preservation due to their antimicrobial properties and eco-friendly synthesis. Furthermore, the study underscores the significance of utilizing natural resources, such as Pimenta dioica, for the development of sustainable and cost-effective nanomaterials with potential therapeutic properties. The results also emphasize the need for further research to optimize the synthesis process, elucidate the mechanisms behind the antimicrobial activity of the AgNPs, and explore their potential applications in various fields.

Keywords

Silver Nanoparticles, Pimenta Dioica, Green Synthesis, Antimicrobial Activity, Nanomedicine